Illuminating the path: mucosal-associated invariant  T cells as key players in ocular immunity

Zhi, Zhaohui; Guo, Ying; Wang, Xiaoxin; Jiang, Wenxi; Sun, Yuanzheng

doi:10.5935/0004-2749.2024-0362

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Illuminating the path: mucosal-associated invariant T cells as key players in ocular immunity

Zhaohui Zhi¹; Ying Guo²; Xiaoxin Wang¹; Wenxi Jiang¹; Yuanzheng Sun^1,2

DOI: 10.5935/0004-2749.2024-0362

ABSTRACT

Mucosal-associated invariant T cells are a distinct subset of immune cells primarily located in mucosal tissues, and their role in ocular disorders has recently garnered increasing attention. This review synthesizes recent research on the roles of mucosal-associated invariant T cells in ophthalmology, focusing on their potential involvement in ocular immune responses, inflammation, and related diseases. By thoroughly analyzing current findings, this paper aims to novel insights that may guide future clinical applications in ophthalmology and address existing knowledge gaps regarding the immunomodulatory roles of mucosal-associated invariant T cells in ocular conditions.

Keywords: Mucosal-associated invariant T cells/immunology; Mucous membrane; Eye diseases/immunology; Immunity, humoral; Autoimmune diseases; Inflammation; Dry eye syndromes/immunology; Eye neoplasms/immunology; Eye infections/immunology; Retinal diseases/immunology

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